Testosterone enanthate injection a chemotherapeutic agent exhibiting activity against Trichomonas vaginalis and other protozoa (including Giardia intestinalis and Entamoeba histolytica), as well as against anaerobic bacteria, namely Bacteroides and Gardnerella vaginalis. Minimum trihomonatsidnaya concentration ranges from 0 3 to 3 mg / ml.
Infections caused by Trichomonas vaginalis, giardiasis, amoebiasis, vaginitis caused by Gardnerella vaginalis, acute necrotizing ulcerative gingivitis (Vincent’s gingivitis).
Hypersensitivity to any component of the drug, severe diseases of the brain and blood, severe renal and hepatic failure.
Acute neurological diseases.
During treatment s not recommended to drink alcoholic beverages (at least for 48 hours after dosing).
Pregnancy and lactation
Application during pregnancy (especially in the first trimester) and lactation should be avoided due to the possible existence of mutagenic properties.
Dosage and administration
. Inside Trichomoniasis : Treatment is carried out by one of the schemes are listed below: Adults : a) 2 g single dose after meal; b) 3 times every 12h 1 g .; c) at 250 mg three times a day for . 5 – 7 daysChildren : 15 mg / kg / day divided in three meals, for 5-7 days. amebiasis : Adults : 500 mg twice a day for 5-10 days; Children : 20 mg / kg . / day, divided into two doses, for 5-10 days Giardiasis : Adults :500 mg twice a day for 5-7 days; Children : 15 mg / kg / day, divided into two doses, for 5 . -7 days Infections caused vaginalis Gardnerella : Adults : a) 500 mg twice a day for 7 days; b) 2 g once. Acute necrotizing ulcerative gingivitis (gingivitis Vincent) : Adults : 500 mg twice daily for 2 days.
usually is well tolerated. Side effects are mild to moderate and do not require discontinuation of therapy. Possible side effects include heartburn, nausea, sometimes vomiting (taking the drug after meals to minimize these effects), skin rash, dizziness, drowsiness, diarrhea, metallic taste and dryness testosterone enanthate injection in the mouth, coated tongue, glossitis and stomatitis, transient moderate severe leucopenia, urethral discomfort and dark urine.
Treatment of patients with acute neurological disorders should be under strict medical supervision.
In the treatment of trichomoniasis in order to avoid re-infection, it is recommended to treat both sexual partners at the same time, even if one of them has no symptoms.
Symptoms: gastrointestinal discomfort (heartburn, nausea, vomiting, diarrhea), dizziness, and possible neurological symptoms (numbness, tingling, paraesthesia and convulsions).
Treatment: gastric lavage and symptomatic treatment.
Interaction with other medicinal products
In an application with alcohol testosterone enanthate injection can cause disulfiramopodobnye reaction. May enhance the anticoagulant effect of warfarin and reduce the clearance of phenytoin and lithium.Phenobarbital can reduce and cimetidine – increase the plasma concentrations of.
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